A new single-cell technology is giving scientists their clearest view yet of immune cell behavior—capturing not just genetic intent, but real-time activity. By measuring RNA and proteins ...

A new single‑cell method, CIPHER‑seq, measures RNA and proteins together to reveal real‑time cytokine signaling.

Since the completion of the Human Genome Project, single linear reference genomes (such as GRCh38) have served as the foundation for biomedical research. However, the genetic backgrounds of human ...

A research team led by Zhen-Xing Endowed Professor Jian Yang at the School of Life Sciences, Westlake University, has ...

Gene expression has to be carefully regulated, or serious problems can arise. Many things can control the expression of genes, including chemical marks that affect the genome without changing the ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

This research, led by Prof. Haichen Wu from the Institute of Chemistry, Chinese Academy of Sciences (CAS), and Prof. Lei Liu from the Institute of High Energy Physics, CAS, alongside their ...